Search on: PRPC PROTEINS 
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Descriptor English:   PrPC Proteins 
Descriptor Spanish:   Proteínas PrPC 
Descriptor Portuguese:   Proteínas PrPC 
Synonyms English:   Cp 33-35
Cp33-35, Scrapie
PrP-sen
PrP sen
Scrapie Amyloid Precursor Protein  
Tree Number:   D12.776.785.340.500
Definition English:   Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity. 
Indexing Annotation English:   PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prion proteins
History Note English:   95; SCRAPIE AMYLOID PRECURSOR PROTEIN was NM 1989-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PY pathogenicity PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32060 
Unique Identifier:   D018621 

Occurrence in VHL:
 

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